ABSTRACT
PURPOSE: Sepsis is a significant cause of morbidity and mortality in the newborn, particularly in preterm. The objective of this study was to analyze the incidence rate, causative pathogens and clinical features of neonatal sepsis in one neonatal intensive care unit (NICU) for 6 years. METHODS: This study was retrospectively performed to review the clinical and laboratory characteristics including sex, gestational age, birth weight, Apgar score, length of hospitalization, length of total parenteral nutrition, presence of central venous catheter, underlying diseases, laboratory findings, microorganisms isolated from blood culture, complications and mortality in 175 patients between January 2003 and December 2008. RESULTS: 1) Sepsis was present in 175 of 3,747 infants for 6 years. There were more gram-positive organisms. 2) The gram-negatives were more prevalent in preterm. There were no significant differences of other clinical features between two groups. 3) Underlying diseases were found in 73.7%, and the most common disease was cardiovascular disease. The most common organisms of gram-positives and gram-negatives were methicillin resistant Staphylococcus aureus (MRSA) and Serratia marcescens. 4) There was statistically significant difference on platelet counts between two groups (P<0.05). 5) Complications were found in 18.3% and septic shock was the most common. MRSA was the most common pathogen in sepsis with complication. 6) The mortality rate was 7.4%. 7) There were differences in monthly blood stream infection/1,000 patient-days. CONCLUSION: The studies about the factors that can influence neonatal sepsis will contribute to decrease the infection rates in NICUs.
Subject(s)
Humans , Infant , Infant, Newborn , Apgar Score , Birth Weight , Cardiovascular Diseases , Central Venous Catheters , Gestational Age , Gram-Negative Bacteria , Gram-Positive Bacteria , Hospitalization , Incidence , Intensive Care, Neonatal , Methicillin Resistance , Methicillin-Resistant Staphylococcus aureus , Parenteral Nutrition, Total , Platelet Count , Retrospective Studies , Rivers , Sepsis , Serratia marcescens , Shock, Septic , Staphylococcus aureusABSTRACT
Liver transplantation is an accepted and successful mode of treatment for pediatric end-stage liver disease. Living related liver transplatation(LRLT) in child has certain potential advantages, such as short cold ischemic time, accurate graft size and vessel diameter match based on elective preoperative preparations. Recently, introduction of microvasular surgery technique to hepatic artery reconstruction has been used, but still remained the possibility of hepatic artery thrombosis. Herein, We report a LRLT case, which showed hepatic artery stenosis postoperatively, successfully dilated by ballon angioplasty technique.
Subject(s)
Child , Humans , Angioplasty , Cold Ischemia , Constriction, Pathologic , Hepatic Artery , Liver , Liver Diseases , Liver Transplantation , Thrombosis , TransplantsABSTRACT
Liver transplantation is an accepted and successful mode of treatment for pediatric end-stage liver disease. A living related liver transplatation(LRLT) in a child has certain potential advantages, such as short cold ischemic time, accurate graft size, and vessel diameter match based on elective preoperative preparations. Recently, microvasular surgery techniques have been introduced in hepatic artery reconstruction but still the possibility of hepatic artery thrombosis remains. Herein, We report an LRLT case, which showed hepatic artery stenosis postoperatively, successfully dilated by balloon angioplasty technique.